Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.

Molecular carcinogenesis - 1 Apr 2007

Chen Jinyun, Sen Subrata, Amos Christopher I, Wei Chongjuan, Jones J Shawn, Lynch Patrick, Frazier Marsha L

Abstract excerpt

Aurora-A kinase is considered a potential cancer susceptibility gene that encodes a centrosome-associated, cell cycle-regulated serine/threonine kinase. We studied two single nucleotide polymorphisms (SNP) in the coding region of Aurora-A, 91T-to-A (F31I) and 169G-to-A (V57I). We studied the influence of these two polymorphisms on age of onset of hereditary nonpolyposis colorectal cancer (HNPCC). Genotyping of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Aurora Kinases

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to Germ-Line Mutation

Share to Protein Serine-Threonine Kinases

Share to White People

Source

Identifiers

PMID: 17219423
DOI: 10.1002/mc.20283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.PMID 17219423Read ↗

Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians.Semantic proximity Read ↗

DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset.Semantic proximity Read ↗

ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States).Semantic proximity Read ↗

Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.Semantic proximity Read ↗

Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk.Semantic proximity Read ↗

Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types.Semantic proximity Read ↗

MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.Semantic proximity Read ↗

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.Semantic proximity Read ↗

Aurora kinases A and B and familial breast cancer risk.Semantic proximity Read ↗

Preferential amplification of AURKA 91A (Ile31) in familial colorectal cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.