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Article

Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk.

Cancer research - 1 May 2005

Kimura Makoto T, Mori Takahiro, Conroy Jeffrey, Nowak Norma J, Satomi Susumu, Tamai Katsuyuki, Nagase Hiroki

Abstract excerpt

STK15/Aurora-A is a serine/threonine kinase essential for chromosome segregation and cytokinesis, and is considered to be a cancer susceptibility gene in mice and humans. Two coding single nucleotide polymorphisms in Aurora-A, 91T>A [phenylalanine/isoleucine (F/I)] and 169G>A [valine/isoleucine (V/I)], create four haplotypes, 91T-169G, 91A-169G, 91T-169A, and 91A-169A. We evaluated the association between these...

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Identifiers

PMID: 15867347
DOI: 10.1158/0008-5472.CAN-04-2149
PMCID: PMC2536656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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