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Article

Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms.

Human genetics - 1 Aug 2001

Trégouet D A, Aubert H, Henry M, Morange P, Visvikis S, Juhan-Vague I, Tiret L

Abstract excerpt

By decreasing plasminogen binding to fibrin surface, the thrombin activatable fibrinolysis inhibitor (TAFI) has been hypothesized to constitute an early marker for atherothrombotic diseases. Previous studies have shown that plasma TAFI levels exhibit a high interindividual variability that is onl...

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PMID: 11511925
DOI: 10.1007/s004390100558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11511925-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms.PMID 11511925Read ↗

Identification of polymorphisms in the promoter and the 3' region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled.Semantic proximity Read ↗

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels.Semantic proximity Read ↗

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Plasma thrombin-activatable fibrinolysis inhibitor antigen concentration and genotype in relation to myocardial infarction in the north and south of Europe.Semantic proximity Read ↗

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Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels.Semantic proximity Read ↗

Genetic and environmental influences on the fibrinolytic system: a twin study.Semantic proximity Read ↗

TAFI gene haplotypes, TAFI plasma levels and future risk of coronary heart disease: the PRIME Study.Semantic proximity Read ↗

Candidate gene analysis of the fibrinogen phenotype reveals the importance of polygenic co-regulation.Semantic proximity Read ↗

Thrombin-activatable fibrinolysis inhibitor (TAFI) levels and its polymorphism rs3742264 are associated with dyslipidemia in a cohort of Brazilian subjects.Semantic proximity Read ↗

Genetic variations in the thrombin-activatable fibrinolysis inhibitor gene and risk of cardiovascular disease: a systematic review and meta-analysis.Semantic proximity Read ↗

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