Article
Genetic and environmental influences on the fibrinolytic system: a twin study.
Thrombosis and haemostasis - 1 Aug 2004
Peetz Dirk, Victor Anja, Adams Petra, Erbes Hilde, Hafner Gerd, Lackner Karl J, Hoehler Thomas
Abstract excerpt
The determination of heritability is a key issue to assess the predictive power of polymorphisms for disease in clinical studies. The aim of this study was to determine the heritability of proteins and activation markers of the fibrinolytic system in a large cohort of healthy twins. Heritability was calculated as 0.76 for thrombin activatable fibrinolysis inhibitor (TAFI), 0.44 for plasminogen activator...
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