Article
Low thrombin activatable fibrinolysis inhibitor activity levels are associated with an increased risk of a first myocardial infarction in men.
Haematologica - 1 Jun 2009
Meltzer Mirjam E, Doggen Carine J M, de Groot Philip G, Meijers Joost C M, Rosendaal Frits R, Lisman Ton
Abstract excerpt
BACKGROUND: Studies on the relation between thrombin activatable fibrinolysis inhibitor (TAFI) and arterial thrombosis have produced conflicting results. TAFI regulates fibrinolysis, but other roles of this inhibitor, including anti-inflammatory properties, have also been demonstrated. DESIGN AND METHODS: We investigated the association between TAFI activity and the risk of myocardial infarction. Additionally, we...
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