Article
Insect nicotinic acetylcholine receptor gene families: from genetic model organism to vector, pest and beneficial species.
Invertebrate neuroscience : IN - 1 Mar 2007
Jones Andrew K, Brown Laurence A, Sattelle David B
Abstract excerpt
Nicotinic acetylcholine receptors (nAChRs) mediate fast synaptic transmission in the insect nervous system and are targets of a major group of insecticides, the neonicotinoids. Analyses of genome sequences have shown that nAChR gene families remain compact in diverse insect species, when compared to their mammalian counterparts. Thus, Drosophila melanogaster and Anopheles gambiae each possess 10 nAChR genes while...
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