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Article

Nicotinic acetylcholine receptor modulator insecticides act on diverse receptor subtypes with distinct subunit compositions.

PLoS genetics - 1 Jan 2022

Lu Wanjun, Liu Zhihan, Fan Xinyu, Zhang Xinzhong, Qiao Xiaomu, Huang Jia

Abstract excerpt

Insect nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels mainly expressed in the central nervous system of insects. They are the directed targets of many insecticides, including neonicotinoids, which are the most widely used insecticides in the world. However, the development of resistance in pests and the negative impacts on bee pollinators affect the application of insecticides...

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Identifiers

PMID: 35045067
DOI: 10.1371/journal.pgen.1009920
PMCID: PMC8803171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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