Article
Diversity of insect nicotinic acetylcholine receptor subunits.
Advances in experimental medicine and biology - 1 Jan 2010
Jones Andrew K, Sattelle David B
Abstract excerpt
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that mediate fast synaptic transmission in the insect nervous system and are targets of a major group of insecticides, the neonicotinoids. They consist of five subunits arranged around a central ion channeL Since the subunit composition determines the functional and pharmacological properties of the receptor the presence of nAChR families...
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