Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A nicotinic acetylcholine receptor mutation (Y151S) causes reduced agonist potency to a range of neonicotinoid insecticides.

Journal of neurochemistry - 1 Nov 2006

Liu Zewen, Williamson Martin S, Lansdell Stuart J, Han Zhaojun, Denholm Ian, Millar Neil S

Abstract excerpt

Neonicotinoid insecticides are potent selective agonists of insect nicotinic acetylcholine receptors (nAChRs). Since their introduction in 1991, resistance to neonicotinoids has been slow to develop, but it is now established in some insect field populations such as the planthopper, Nilaparvata lugens, a major rice pest in many parts of Asia. We have reported recently the identification of a target-site mutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Insecta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insecticide Resistance

Share to Insecticides

Share to Membrane Potentials

Share to Oocytes

Share to Receptors, Nicotinic

Share to Xenopus laevis

Source

Identifiers

PMID: 16981889
DOI: 10.1111/j.1471-4159.2006.04167.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A nicotinic acetylcholine receptor mutation (Y151S) causes reduced agonist potency to a range of neonicotinoid insecticides.PMID 16981889Read ↗

Imidacloprid acts as an antagonist on insect nicotinic acetylcholine receptor containing the Y151M mutation.Semantic proximity Read ↗

Heteromeric co-assembly of two insect nicotinic acetylcholine receptor alpha subunits: influence on sensitivity to neonicotinoid insecticides.Semantic proximity Read ↗

The mode of action of a nitroconjugated neonicotinoid and the effects of target site mutation Y151S on its potency.Semantic proximity Read ↗

Combinatorial mutations in loops D and F strongly influence responses of the alpha7 nicotinic acetylcholine receptor to imidacloprid.Semantic proximity Read ↗

Identification of key amino acid differences between Cyrtorhinus lividipennis and Nilaparvata lugens nAChR α8 subunits contributing to neonicotinoid sensitivity.Semantic proximity Read ↗

The insecticidal activity and action mode of an imidacloprid analogue, 1-(3-pyridylmethyl)-2-nitroimino-imidazolidine.Semantic proximity Read ↗

Insect nicotinic acetylcholine receptor gene families: from genetic model organism to vector, pest and beneficial species.Semantic proximity Read ↗

Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae.Semantic proximity Read ↗

Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster.Semantic proximity Read ↗

Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the alpha4beta2 nicotinic acetylcholine receptor.Semantic proximity Read ↗

Effect of the R80T mutation in the nicotinic acetylcholine receptor β1 subunit on the susceptibility of Frankliniella occidentalis (Pergande) to neonicotinoids.Semantic proximity Read ↗

Mutation V65I in the β1 Subunit of the Nicotinic Acetylcholine Receptor Confers Neonicotinoid and Sulfoxaflor Resistance in Insects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.