Article
Structure and diversity of insect nicotinic acetylcholine receptors.
Pest management science - 1 Oct 2001
Tomizawa M, Casida J E
Abstract excerpt
The nicotinic acetylcholine receptor (nAChR) is an agonist-regulated ion-channel complex responsible for rapid neurotransmission. The vertebrate nAChR, assembled from five homologous subunits, penetrates the synaptic membrane. Different subunit combinations lead to receptor subtypes with distinctive pharmacological profiles. In comparison with mammalian nAChRs, the insect receptor is poorly understood relative to...
Topics
- Animals
- Aphids
- Drosophila
- Genetic Variation
- Imidazoles
- Insecticides
- Molecular Structure
- Neonicotinoids
- Nitro Compounds
- Plants
- Receptors, Nicotinic
- Structure-Activity Relationship
- Vertebrates
