Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The nicotinic acetylcholine receptor subunit Mdalpha6 from Musca domestica is diversified via post-transcriptional modification.

Insect molecular biology - 1 Jun 2007

Gao J-R, Deacutis J M, Scott J G

Abstract excerpt

Recent studies showed that deletion of a nicotinic acetylcholine receptor (nAChR) subunit gene, Dalpha6 in Drosophila melanogaster results in a strain that is resistant to spinosad, indicating that Dalpha6 is important for the toxic action of this insecticide. To determine if spinosad resistance in house flies was due to a mutation(s) of Mdalpha6 (the orthologue of Dalpha6 from house flies), cDNAs were cloned and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Drug Combinations
Share to Houseflies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insecticide Resistance

Share to Macrolides

Share to Protein Subunits

Share to Receptors, Nicotinic

Share to RNA Processing, Post-Transcriptional

Source

Identifiers

PMID: 17439546
DOI: 10.1111/j.1365-2583.2007.00730.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The nicotinic acetylcholine receptor subunit Mdalpha6 from Musca domestica is diversified via post-transcriptional modification.PMID 17439546Read ↗

In vivo functional analysis of the Drosophila melanogaster nicotinic acetylcholine receptor Dα6 using the insecticide spinosad.Semantic proximity Read ↗

RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation.Semantic proximity Read ↗

Transcriptome Analysis of an Insecticide Resistant Housefly Strain: Insights about SNPs and Regulatory Elements in Cytochrome P450 Genes.Semantic proximity Read ↗

Diversity of insect nicotinic acetylcholine receptor subunits.Semantic proximity Read ↗

Insect nicotinic acetylcholine receptor gene families: from genetic model organism to vector, pest and beneficial species.Semantic proximity Read ↗

Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides.Semantic proximity Read ↗

Structure and diversity of insect nicotinic acetylcholine receptors.Semantic proximity Read ↗

Nicotinic acetylcholine receptor subunit α6 associated with spinosad resistance in Rhyzopertha dominica (Coleoptera: Bostrichidae).Semantic proximity Read ↗

Knockdown resistance to DDT and pyrethroids in the house fly (Diptera: Muscidae): from genetic trait to molecular mechanism.Semantic proximity Read ↗

Transcriptional diversity and allelic variation in nicotinic acetylcholine receptor subunits of the red flour beetle, Tribolium castaneum.Semantic proximity Read ↗

Identification and characterization of mutations in housefly (Musca domestica) acetylcholinesterase involved in insecticide resistance.Semantic proximity Read ↗

A spinosyn-sensitive Drosophila melanogaster nicotinic acetylcholine receptor identified through chemically induced target site resistance, resistance gene identification, and heterologous expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.