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Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster.

Insect biochemistry and molecular biology - 1 Apr 2021

Perry Trent, Chen Wei, Ghazali Razi, Yang Ying Ting, Christesen Danielle, Martelli Felipe, Lumb Chris, Bao Luong Hang Ngoc, Mitchell Judith, Holien Jessica K, Parker Michael W, Sparks Thomas C, Batterham Philip

Abstract excerpt

Insecticides remain valuable tools for the control of insect pests that significantly impact human health and agriculture. A deeper understanding of insecticide targets is important in maintaining this control over pests. Our study systematically investigates the nicotinic acetylcholine receptor (nAChR) gene family, in order to identify the receptor subunits critical to the insect response to insecticides from...

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PMID: 33548485
DOI: 10.1016/j.ibmb.2021.103547

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