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Article

Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2015

Heghinian Mari D, Mejia Monica, Adams David J, Godenschwege Tanja A, Marí Frank

Abstract excerpt

Nicotinic acetylcholine receptors (nAChRs) play a pivotal role in synaptic transmission of neuronal signaling pathways and are fundamentally involved in neuronal disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. In vertebrates, cholinergic pathways can be selectively inhibited by α-conotoxins; we show that in the model organism Drosophila, the cholinergic component of the giant...

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Identifiers

PMID: 25466886
DOI: 10.1096/fj.14-262733
PMCID: PMC4422358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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