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Article

Comparative analysis of flow cytometric techniques in assessment of ZAP-70 expression in relation to IgVH mutational status in chronic lymphocytic leukemia.

American journal of clinical pathology - 1 Feb 2007

Chen Yi-Hua, Peterson LoAnn C, Dittmann David, Evens Andrew, Rosen Steven, Khoong Adela, Shankey T Vincent, Forman Meryl, Gupta Rohit, Goolsby Charles L

Abstract excerpt

We compared 1 subjective and 5 objective flow cytometric methods to evaluate zeta-associated protein (ZAP-70) expression in relation to immunoglobulin heavy-chain variable-region (IgVH) gene mutational status in 154 samples from 125 patients with chronic lymphocytic leukemia (CLL). ZAP-70 expression determined by all methods used correlated with IgVH gene mutational status, but none of them demonstrated high...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Genes, Immunoglobulin Heavy Chain

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 17210531
DOI: 10.1309/230199FLE32ATUB0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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