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Article

Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function.

American journal of respiratory and critical care medicine - 15 Mar 2007

Wilk Jemma B, Herbert Alan, Shoemaker Christina M, Gottlieb Daniel J, Karamohamed Samer

Abstract excerpt

RATIONALE: Previously reported linkage to FEV(1) (LOD score = 5.0) on 6q27 in the Framingham Heart Study (FHS) led us to explore a candidate gene, SMOC2, at 168.6 Mb. OBJECTIVES: We tested association between SMOC2 polymorphisms and FEV(1) and FVC in unrelated FHS participants. METHODS: Twenty single-nucleotide polymorphisms (SNPs) around SMOC2 were genotyped in 1,734 subjects. MEASUREMENTS AND MAIN RESULTS: SNP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17204727
DOI: 10.1164/rccm.200601-110OC
PMCID: PMC1899283

Genes

FEV
SMOC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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