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Genetic Loci Influencing Lung Function: A Genomewide Scan in the Framingham Study

1 Mar 2002

Abstract excerpt

Prior studies have found cross-sectional lung function to be highly heritable. In the present study, we used a 10-cM genome-wide scan of 1,578 members of 330 families participating in the Framingham Study to test for linkage of genetic markers to level of lung function as determined by spirometry during middle age. At this age, lung function measures may reflect the effects of genes influencing lung growth and...

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PMID: 11897646
DOI: 10.1164/ajrccm.165.6.2102057

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