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Article

Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study.

Human molecular genetics - 1 Nov 2003

Wilk Jemma B, DeStefano Anita L, Joost Oscar, Myers Richard H, Cupples L Adrienne, Slater Karen, Atwood Larry D, Heard-Costa Nancy L, Herbert Alan, O'Connor George T, Gottlieb Daniel J

Abstract excerpt

Spirometric measures of pulmonary function have been shown to be highly heritable and evidence for major genes influencing forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) have been reported. A genome scan of pulmonary traits in the Framingham Heart Study identified a region on chromosome 6qter with evidence for linkage to FEV1 and the FEV1/FVC ratio. For this study, additional markers were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12966033
DOI: 10.1093/hmg/ddg311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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