Article
Genetic variants associated with lung function: the long life family study.
Respiratory research - 1 Nov 2014
Thyagarajan Bharat, Wojczynski Mary, Minster Ryan L, Sanders Jason, Barral Sandra, Christiansen Lene, Barr R Graham, Newman Anne
Abstract excerpt
BACKGROUND: Reduced forced expiratory volume in 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) are strong predictors of mortality and lung function is higher among individuals with exceptional longevity. However, genetic factors associated with lung function in individuals with exceptional longevity have not been identified. METHOD: We conducted a genome wide association study (GWAS) to...
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