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Article

Association analysis of the SHC1 gene locus with longevity in the Japanese population.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2003

Kamei Hidehiko, Adati Naoki, Arai Yasumichi, Yamamura Ken, Takayama Michiyo, Nakazawa Susumu, Ebihara Yoshinori, Gondo Yasuyuki, Akechi Mizuho, Noguchi Toshihide, Hirose Nobuyoshi, Sakaki Yoshiyuki, Kojima Toshio

Abstract excerpt

The SHC1 gene encodes a signaling and transforming protein that has been implicated in the aging process in worms and mammals. In this study we examined 230 Japanese centenarians and 180 healthy younger controls and looked at the SHC1 locus as a candidate region that may be associated with longevity. We identified 12 single nucleotide polymorphisms (SNPs) within a 10-kb region encompassing the entire SHC1 gene...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14530863
DOI: 10.1007/s00109-003-0485-0

Genes

SHC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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