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Article

The Thr715Pro polymorphism of the P-selectin gene is not associated with ischemic stroke risk.

Stroke - 1 Feb 2007

Ferrari Julia, Rieger Sandra, Endler Georg, Greisenegger Stefan, Funk Marion, Scholze Thomas, Lang Wilfried, Lalouschek Wolfgang, Mannhalter Christine

Abstract excerpt

BACKGROUND AND PURPOSE: A Thr>Pro polymorphism at codon 715 in the coding region of the P-selectin gene has recently been described. Individuals carrying the Pro715 allele were reported to have a reduced risk of myocardial infarction. A possible association of this polymorphism with the risk of ischemic stroke is currently under discussion. METHODS: We investigated the prevalence of the 715 Thr>Pro polymorphism...

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Identifiers

PMID: 17204688
DOI: 10.1161/01.STR.0000254475.43533.dd

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Thr715Pro polymorphism of the P-selectin gene is not associated with ischemic stroke risk.PMID 17204688Read ↗

P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.Semantic proximity Read ↗

Association of the single-nucleotide polymorphism and haplotype of the P-selectin gene with ischemic stroke.Semantic proximity Read ↗

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease.Semantic proximity Read ↗

807C/T polymorphism in the platelet glycoprotein Ia gene in young patients with ischemic stroke of undetermined etiology.Semantic proximity Read ↗

The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction.Semantic proximity Read ↗

The association of L-selectin polymorphisms with L-selectin serum levels and risk of ischemic stroke.Semantic proximity Read ↗

The Ser290Asn and Thr715Pro Polymorphisms of the SELP Gene Are Associated with A Lower Risk of Developing Acute Coronary Syndrome and Low Soluble P-Selectin Levels in A Mexican Population ‡.Semantic proximity Read ↗

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