Article
Ser128Arg E-selectin and Thr715Pro P-selectin polymorphisms and severe preeclampsia.
The Journal of reproductive medicine - 1 Sept 2007
Derzbach László, Balogh Adám, Bokodi Géza, Vásárhelyi Barna, Rigó János
Abstract excerpt
OBJECTIVE: To investigate the association of functional E and P selectin polymorphisms with severe preeclampsia. STUDY DESIGN: P-selectin Thr715Pro and E-selectin Serl28Arg polymorphism were determined with the polymerase chain reaction in 126 women with severe preeclampsia and in 106 healthy pregnant women. Genotype distribution and allele prevalence of both groups were compared. Regression analysis was used to...
Topics
- Adolescent
- Adult
- Case-Control Studies
- E-Selectin
- Female
- Gene Frequency
- HELLP Syndrome
- Humans
- Hungary
- P-Selectin
- Polymorphism, Single Nucleotide
- Pre-Eclampsia