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Article

EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase.

Journal of neurochemistry - 1 Aug 2007

Rajamanickam Jeyaganesh, Palmada Monica, Lang Florian, Boehmer Christoph

Abstract excerpt

EAAT4 (SLC1A6) is a Purkinje-Cell-specific post-synaptic excitatory amino acid transporter that plays a major role in clearing synaptic glutamate. EAAT4 abundance and function is known to be modulated by the serum and glucocorticoid inducible kinase (SGK) 1 but the precise mechanism of kinase action has not been defined yet. The present work aims to identify the molecular mechanism of EAAT4 modulation by the...

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Source

Identifiers

PMID: 17442044
DOI: 10.1111/j.1471-4159.2007.04585.x

Genes

SGK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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