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Article

Role of Sgk1 in salt and potassium homeostasis.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jan 2005

Vallon Volker, Wulff Peer, Huang Dan Yang, Loffing Johannes, Völkl Harald, Kuhl Dietmar, Lang Florian

Abstract excerpt

Aldosterone plays a pivotal role in NaCl and K(+) homeostasis by stimulation of Na(+) reabsorption and K(+) secretion in the aldosterone-sensitive distal nephron (ASDN). Recent studies demonstrated that the serum- and glucocorticoid-regulated kinase 1 (Sgk1) is induced by aldosterone in the ASDN and that polymorphisms of the kinase associate with arterial blood pressure in normotensive subjects. This review...

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Identifiers

PMID: 15590995
DOI: 10.1152/ajpregu.00369.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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