Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of a third conserved phosphorylation site in SGK1.

The Journal of biological chemistry - 6 Feb 2009

Chen Wei, Chen Yue, Xu Bing-e, Juang Yu-Chi, Stippec Steve, Zhao Yingming, Cobb Melanie H

Abstract excerpt

SGK1 (serum- and glucocorticoid-induced kinase 1) is a member of the AGC branch of the protein kinase family. Among well described functions of SGK1 is the regulation of epithelial transport through phosphorylation of the ubiquitin protein ligase Nedd4-2 (neuronal precursor cell expressed develop...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Endosomal Sorting Complexes Required for Transport
Share to Immediate-Early Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Minor Histocompatibility Antigens

Share to Nedd4 Ubiquitin Protein Ligases

Share to Proto-Oncogene Proteins c-akt

Share to Ubiquitin-Protein Ligases

Share to WNK Lysine-Deficient Protein Kinase 1

Source

Open in PubMed Open full text

Identifiers

PMID: 19068477
DOI: 10.1074/jbc.M807502200
PMCID: PMC2635031

Genes

SGK1
WNK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19068477-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of a third conserved phosphorylation site in SGK1.PMID 19068477Read ↗

SGK1 in Human Cancer: Emerging Roles and MechanismsSemantic proximity Read ↗

EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase.Semantic proximity Read ↗

Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth.Semantic proximity Read ↗

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.Semantic proximity Read ↗

Sgk1, a cell survival response in neurodegenerative diseasesSemantic proximity Read ↗

Serum and Glucocorticoid-Inducible Kinase 1 (SGK1) in NSCLC TherapySemantic proximity Read ↗

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.Semantic proximity Read ↗

SGK1, a Critical Regulator of Immune Modulation and Fibrosis and a Potential Therapeutic Target in Chronic Graft-Versus-Host DiseaseSemantic proximity Read ↗

A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct.Semantic proximity Read ↗

Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation.Semantic proximity Read ↗

The Multifaceted Role of S6K1 in Cellular Regulation: Structural Insights, Isoform-Specific Functions, and Therapeutic PotentialSemantic proximity Read ↗

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.