Article
A single nucleotide polymorphism genotyping method using phosphate-affinity polyacrylamide gel electrophoresis.
Analytical biochemistry - 15 Feb 2007
Kinoshita Eiji, Kinoshita-Kikuta Emiko, Koike Tohru
Abstract excerpt
To date, various methods have been developed to facilitate the genotyping of a single nucleotide polymorphism (SNP) for aiding in the diagnosis and treatment of inherited diseases. The most commonly used method for SNP genotyping is an allele-specific hybridization procedure using an expensive fluorochrome-labeled oligonucleotide probe and a specialized fluorescence analyzer. Here, we introduce a simple and...
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