Article
Zn(II)-cyclen polyacrylamide gel electrophoresis for SNP detection.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Kinoshita-Kikuta Emiko, Kinoshita Eiji, Koike Tohru
Abstract excerpt
We introduce a method for the detection of single-nucleotide polymorphisms (SNPs) by polyacrylamide gel electrophoresis (PAGE) with an additive Zn2+-cyclen complex (cyclen is 1,4,7,10-tetraazacyclododecane), called "Zn2+-cyclen-PAGE." The method is based on the difference in mobility of mutant DN...
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