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Article

Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis.

Development (Cambridge, England) - 1 Feb 2007

Shibutani Shusaku, Swanhart Lisa M, Duronio Robert J

Abstract excerpt

The initiation and maintenance of G1 cell cycle arrest is a key feature of animal development. In the Drosophila ectoderm, G1 arrest first appears during the seventeenth embryonic cell cycle. The initiation of G1(17) arrest requires the developmentally-induced expression of Dacapo, a p27-like Cyclin E-Cdk2 inhibitor. The maintenance of G1(17) arrest requires Rbf1-dependent repression of E2f1-regulated replication...

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Identifiers

PMID: 17185321
DOI: 10.1242/dev.02738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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