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Article

New approach for rapid detection of known hemoglobin variants using LC-MS/MS combined with a peptide database.

Journal of mass spectrometry : JMS - 1 Mar 2007

Basilico F, Di Silvestre D, Sedini S, Petretto A, Levreri I, Melioli G, Farina C, Mori F, Mauri P L

Abstract excerpt

The identification of hemoglobin (Hb) variants is usually performed by means of different analytical steps and methodologies. Phenotypic methods, such as gel electrophoresis and high performance liquid chromatography, are used to detect the different electrophoretic or chromatographic behaviors of hemoglobin variants in comparison to HbA0 used as a control. These data often need to be combined with mass...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 17177235
DOI: 10.1002/jms.1160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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