Advanced analytical methods for hemoglobin variants.

doi:10.1016/s1570-0232(02)00558-5

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Article

Advanced analytical methods for hemoglobin variants.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 5 Dec 2002

Wada Yoshinao

Abstract excerpt

Hemoglobin variants are the protein mutations most often encountered in the clinical scene. They have been useful for developing methods to analyze mutant proteins because of their size and ease of collection in large amounts. Improvements in analytical methods have been directed toward higher resolution in electrophoresis and shorter elution times in chromatography. More importantly, in the last 20 years,...

Topics

Chromatography
Electrophoresis, Capillary
Hemoglobins
Mass Spectrometry
Molecular Weight
Mutation

Source

Open in PubMed

Identifiers

PMID: 12450664
DOI: 10.1016/s1570-0232(02)00558-5

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