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Article

Mass spectrometry: a tool for enhanced detection of hemoglobin variants.

Clinical chemistry - 1 Jan 2008

Kleinert Peter, Schmid Marlis, Zurbriggen Karin, Speer Oliver, Schmugge Markus, Roschitzki Bernd, Durka Silke S, Leopold Urs, Kuster Thomas, Heizmann Claus W, Frischknecht Hannes, Troxler Heinz

Abstract excerpt

BACKGROUND: More than 900 hemoglobin (Hb) variants are currently known. Common techniques used in Hb analysis are electrophoretic and chromatographic assays. In our laboratory, we routinely apply chromatographic methods. To ascertain whether Hb variants are missed with our procedures, we additionally analyzed all samples with mass spectrometry (MS). METHODS: Database evaluation was performed using all entries...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17932132
DOI: 10.1373/clinchem.2007.089961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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