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Article

Automated analysis of hemoglobin variants using nanoLC-MS and customized databases.

Journal of proteome research - 5 Jul 2013

Das Rajdeep, Mitra Gopa, Mathew Boby, Ross Cecil, Bhat Vijay, Mandal Amit Kumar

Abstract excerpt

Unambiguous analysis of hemoglobin variants is critical in the diagnosis of hemoglobinopathies. In diagnostic laboratories, alkaline gel electrophoresis and automated HPLC are used in identifying variants. In specific instances, comigration of hemoglobin variant bands in gel and coelution of different variants or elution of variants with unmatched library information in HPLC can result in ambiguities in...

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PMID: 23692286
DOI: 10.1021/pr4000625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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