Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry.

Blood cells, molecules & diseases - 1 Jan 2000

Wild B J, Green B N, Cooper E K, Lalloz M R, Erten S, Stephens A D, Layton D M

Abstract excerpt

The precise identification of human hemoglobin variants, over 700 human hemoglobin variants are known, is essential for prediction of their clinical and genetic significance. A systematic approach to their rapid identification is described. Traditionally this requires protein or DNA characterization which entails lengthy analytical procedures. To overcome these obstacles a rapid approach to variant hemoglobin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Globins

Share to Hemoglobins, Abnormal

Share to Methods

Share to Specimen Handling

Share to Spectrometry, Mass, Electrospray Ionization

Source

Identifiers

PMID: 11482884
DOI: 10.1006/bcmd.2001.0430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry.PMID 11482884Read ↗

Phenotype determination of hemoglobinopathies by mass spectrometry.Semantic proximity Read ↗

Electrospray tandem mass spectrometry of intact beta-chain hemoglobin variants.Semantic proximity Read ↗

Advanced analytical methods for hemoglobin variants.Semantic proximity Read ↗

Mass spectrometry: a tool for enhanced detection of hemoglobin variants.Semantic proximity Read ↗

Hemoglobin variant analysis of whole blood and dried blood spots by MS.Semantic proximity Read ↗

Advances in hemoglobinopathy detection and identification.Semantic proximity Read ↗

Rapid and specific detection of clinically significant haemoglobinopathies using electrospray mass spectrometry-mass spectrometry.Semantic proximity Read ↗

Accurate mass measurement by electrospray ionization quadrupole mass spectrometry: detection of variants differing by <6 Da from normal in human hemoglobin heterozygotes.Semantic proximity Read ↗

Automated analysis of hemoglobin variants using nanoLC-MS and customized databases.Semantic proximity Read ↗

High pressure liquid chromatography and electrospray ionization mass spectrometry are advantageously integrated into a two-levels approach to detection and identification of haemoglobin variants.Semantic proximity Read ↗

Electrospray ionization mass analysis of normal and genetic variants of human serum albumin.Semantic proximity Read ↗

Unstable Hemoglobin Variants: Molecular Mechanisms, Clinical Phenotypes, and a Practical Diagnostic and Management Approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.