Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment.

The Journal of cell biology - 1 Oct 1991

Moran P, Caras I W

Abstract excerpt

The COOH terminus of decay-accelerating factor (DAF) contains a signal that directs glycophosphatidylinositol (GPI) membrane anchor attachment in a process involving concerted proteolytic removal of 28 COOH-terminal residues. At least two elements are required for anchor addition: a COOH-terminal hydrophobic domain and a cleavage/attachment site located NH2-terminal to it, requiring a small amino acid as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Line
Share to Cell Membrane

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Peptide Fragments

Source

Open in PubMed Open full text

Identifiers

PMID: 1717483
DOI: 10.1083/jcb.115.2.329
PMCID: PMC2289147

Genes

GPI
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment.PMID 1717483Read ↗

Carboxyl terminus structural requirements for glycosyl-phosphatidylinositol anchor addition to cell surface proteins.Semantic proximity Read ↗

Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition.Semantic proximity Read ↗

Active site determination of Gpi8p, a caspase-related enzyme required for glycosylphosphatidylinositol anchor addition to proteins.Semantic proximity Read ↗

A conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidase.Semantic proximity Read ↗

Activation of the PDGF β Receptor by a Persistent Artificial Signal Peptide.Semantic proximity Read ↗

Prediction of potential GPI-modification sites in proprotein sequences.Semantic proximity Read ↗

Molecular requirements for attachment of the glycosylphosphatidylinositol anchor to the human alpha folate receptor.Semantic proximity Read ↗

In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the EndotheliumSemantic proximity Read ↗

Biosynthesis of surfactant protein C (SP-C). Sorting of SP-C proprotein involves homomeric association via a signal anchor domain.Semantic proximity Read ↗

The C-terminus of glycosylphosphatidylinositol-specific phospholipase D is essential for biological activity.Semantic proximity Read ↗

Addition of a glycophosphatidylinositol to acetylcholinesterase. Processing, degradation, and secretion.Semantic proximity Read ↗

Functional analysis of T-cell mutants defective in the biosynthesis of glycosylphosphatidylinositol anchor. Relative importance of glycosylphosphatidylinositol anchor versus N-linked glycosylation in T-cell activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.