Article
Carboxyl terminus structural requirements for glycosyl-phosphatidylinositol anchor addition to cell surface proteins.
Journal of cell science - 1 Jul 1993
Beghdadi-Rais C, Schreyer M, Rousseaux M, Borel P, Eisenberg R J, Cohen G H, Bron C, Fasel N
Abstract excerpt
Glycosyl phosphatidylinositol (GPI)-anchored proteins contain in their COOH-terminal region a peptide segment that is thought to direct glycolipid addition. This signal has been shown to require a pair of small amino acids positioned 10-12 residues upstream of an hydrophobic C-terminal domain. We...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Surface
- Base Sequence
- DNA, Complementary
- Glycoproteins
- Glycosylphosphatidylinositols
- HeLa Cells
- Humans
- Membrane Glycoproteins
- Membrane Proteins
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Phosphatidylinositol Diacylglycerol-Lyase