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Article

Addition of a glycophosphatidylinositol to acetylcholinesterase. Processing, degradation, and secretion.

The Journal of biological chemistry - 27 Jul 2001

Coussen F, Ayon A, Le Goff A, Leroy J, Massoulié J, Bon S

Abstract excerpt

We introduced various mutations and modifications in the GPI anchoring signal of rat acetylcholinesterase (AChE). 1) The resulting mutants, expressed in transiently transfected COS cells, were initially produced at the same rate, in an active form, but the fraction of GPI-anchored AChE and the steady state level of AChE activity varied over a wide range. 2) Productive interaction with the GPI addition machinery...

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Source

Identifiers

PMID: 11337488
DOI: 10.1074/jbc.M010817200

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Addition of a glycophosphatidylinositol to acetylcholinesterase. Processing, degradation, and secretion.PMID 11337488Read ↗

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