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Article

Molecular requirements for attachment of the glycosylphosphatidylinositol anchor to the human alpha folate receptor.

Journal of cellular biochemistry - 1 Jan 1999

Tomassetti A, Bottero F, Mazzi M, Miotti S, Colnaghi M I, Canevari S

Abstract excerpt

The alpha isoform of the folate receptor (FR) is a 38-KDa glycosylphosphatidylinositol (GPI) protein which mediates the internalization of folates. The FR amino acid sequence has features typical of GPI-linked proteins, including the presence of a hydrophobic carboxyl-terminus, a hinge region, and a stretch of small and uncharged amino acids. Substitution of predicted cleavage/attachment Ser234 with arginine or...

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Source

Identifiers

PMID: 10025672
DOI: 10.1002/(sici)1097-4644(19990101)72:1<111::aid-jcb12>3.0.co;2-1

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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