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Article

Cyclooxygenase-2 polymorphisms in Parkinson's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007

Håkansson Anna, Bergman Olle, Chrapkowska Cecilia, Westberg Lars, Belin Andrea Carmine, Sydow Olof, Johnels Bo, Olson Lars, Holmberg Björn, Nissbrandt Hans

Abstract excerpt

Accumulating evidence indicate that cyclooxygenase-2 (COX-2) is of pathophysiological importance for the neurodegeneration in Parkinson's disease (PD). For example, in a large epidemiological study, use of NSAIDs was associated with a lower risk of PD. Genetic variants of the COX-2 gene might therefore influence the risk of developing the disease. The genotype distribution of four common single nucleotide...

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PMID: 17171651
DOI: 10.1002/ajmg.b.30449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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