Article
Aldehyde dehydrogenase 2 genetic variations may increase susceptibility to Parkinson's disease in Han Chinese population.
Neurobiology of aging - 1 Sept 2015
Zhang Xiong, Ye Yang-Lie, Wang Ya-Nan, Liu Fang-Fang, Liu Xue-Xia, Hu Bei-Lei, Zou Ming, Zhu Jian-Hong
Abstract excerpt
Genetic variations of ALDH2, encoding aldehyde dehydrogenase-2 which regulates aldehyde oxidation in the brain, have been recently suggested to impact on the association of pesticide exposure with Parkinson's disease (PD). However, the link between ALDH2 polymorphism and PD remains elusive. In the present study, tag-single nucleotide polymorphisms of ALDH2, including rs4767944, rs441, and rs671, were extracted...
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