Article
Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease.
Neuroscience letters - 11 Nov 2004
Huerta Cecilia, Alvarez Victoria, Mata Ignacio F, Coto Eliecer, Ribacoba René, Martínez Carmen, Blázquez Marta, Guisasola Luis M, Salvador Carlos, Lahoz Carlos H, Peña Joaquín
Abstract excerpt
Parkinson's disease (PD) is a complex disorder characterized by the progressive degeneration of dopaminergic neurons in the midbrain. Late-onset Alzheimer's disease (LOAD) is the most common cause of dementia in the elderly, affecting about 5% of the population older than 65 years. Several works have demonstrated the involvement of inflammation in the pathogenesis of both, PD and LOAD. Genetic susceptibility to...
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