Article
NAT2 polymorphisms and risk for Parkinson's disease: a systematic review and meta-analysis.
Expert opinion on drug metabolism & toxicology - 1 Aug 2016
Jiménez-Jiménez Félix Javier, Alonso-Navarro Hortensia, García-Martín Elena, Agúndez José A G
Abstract excerpt
INTRODUCTION: Several studies suggested a possible association between certain polymorphisms in the N-acetyl-transferase 2 (NAT2) gene (which encodes a very important enzyme involved in xenobiotic metabolism) and the risk for Parkinson's disease (PD). As the results of studies on this issue are controversial, we conducted a systematic review and a meta-analysis of eligible studies on this putative association....
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