Article
Association of TLR9 polymorphisms with sporadic Parkinson's disease in Chinese Han population.
The International journal of neuroscience - 1 Jan 2016
Zhu Konghua, Teng Jijun, Zhao Jing, Liu Hongxin, Xie Anmu
Abstract excerpt
Previous studies have acknowledged that inflammatory reaction has implicated in Parkinson's disease (PD) pathogenesis nowadays. Toll-like receptors (TLRs), as key players in the inflammatory reaction, play a pivotal role in the PD pathogenesis and accumulating evidences have shown that TLRs are increased in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of PD. Therefore, the present study aimed to...
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