Article
Polymorphisms in genes related to bacterial lipopolysaccharide/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer.
Digestive diseases and sciences - 1 Jan 2007
Kato Ikuko, Canzian Federico, Plummer Martyn, Franceschi Silvia, van Doorn Leen-Jan, Vivas Jorge, Lopez Gladys, Lu Yanhui, Gioia-Patricola Lydie, Severson Richard K, Schwartz Ann G, Muñoz Nubia
Abstract excerpt
As Helicobacter pylori (HP) is a Gram-negative bacterium, we investigated the associations between several functional polymorphisms in genes involved in lipopolysaccharide (LPS) signaling and the prevalence of various stages of gastric premalignant lesions in a Venezuelan population. The two NOD2 polymorphisms, del3020insC and Gly908Arg, were too infrequent to study their associations with gastric lesions. The...
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