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Article

Genetic polymorphisms in mediators of inflammation and gastric precancerous lesions.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 2008

Canzian Federico, Franceschi Silvia, Plummer Martyn, van Doorn Leen-Jan, Lu Yanhui, Gioia-Patricola Lydie, Vivas Jorge, Lopez Gladys, Severson Richard K, Schwartz Ann G, Muñoz Nubia, Kato Ikuko

Abstract excerpt

Chronic inflammation induced by Helicobacter pylori is a key process in gastric carcinogenesis. We hypothesized that genetic polymorphisms in important mediators of H. pylori-induced inflammation may influence the risk of developing various grades of precancerous lesions. We studied the associations between single nucleotide polymorphisms (SNPs) in cyclooxygenase 1 and 2 (PTGS1 and PTGS2), inducible nitric oxide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18287876
DOI: 10.1097/CEJ.0b013e3282b6fd88

Genes

IFNG
IFNGR1
PTGS1
PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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