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Article

Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer.

BMC cancer - 26 Apr 2007

Garza-Gonzalez Elvira, Bosques-Padilla Francisco J, Mendoza-Ibarra Sandra I, Flores-Gutierrez Juan P, Maldonado-Garza Hector J, Perez-Perez Guillermo I

Abstract excerpt

BACKGROUND: The intensity of the inflammation induced by Helicobacter pylori colonization is associated with the development of distal gastric cancer (GC). The host response to H. pylori has been related to genetic polymorphisms that influence both innate and adaptive immune responses.Our aim was to investigate whether the presence of the TLR4 Asp299Gly, TLR4 Thr399Ile and IL-8-251 A/T polymorphisms had any...

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Identifiers

PMID: 17462092
DOI: 10.1186/1471-2407-7-70
PMCID: PMC1868033

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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