Article
Genetic polymorphisms in anti-inflammatory cytokine signaling and the prevalence of gastric precancerous lesions in Venezuela.
Cancer causes & control : CCC - 1 Nov 2006
Kato Ikuko, Canzian Federico, Franceschi Silvia, Plummer Martyn, van Doorn Leen-Jan, Lu Yanhui, Gioia-Patricola Lydie, Vivas Jorge, Lopez Gladys, Severson Richard K, Schwartz Ann G, Muñoz Nubia
Abstract excerpt
OBJECTIVES: The aim of the study was to assess the effects of genetic polymorphisms in anti-inflammatory mediators, i.e., IL10, IL4 and IL4R on the prevalence of gastric precancerous lesions and their interactions with other environmental factors. METHODS: The study population consisted of 2,033 Venezuelan subjects known to have extremely high Helicobacter Pylori (HP) infection rates. The odds ratios (OR) and 95%...
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