Article
Host-bacterial interaction in the development of gastric precancerous lesions in a high risk population for gastric cancer in Venezuela.
International journal of cancer - 1 Oct 2006
Kato Ikuko, van Doorn Leen-Jan, Canzian Federico, Plummer Martyn, Franceschi Silvia, Vivas Jorge, Lopez Gladys, Lu Yanhui, Gioia-Patricola Lydie, Severson Richard K, Schwartz Ann G, Muñoz Nubia
Abstract excerpt
Helicobacter pylori (HP) infection affects over 50% of the world's population. The prevalence is over 90% in populations at high risk for gastric cancer, but clinical outcomes of the infection are highly variable and thus host genetic factors have been suggested to play a role in its outcomes in addition to bacterial factors. In this study, we examined the effects of common functional genetic polymorphisms of...
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