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Article

RASSF1A methylation and K-ras and B-raf mutations and recurrent endometrial cancer.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Mar 2007

Pijnenborg J M A, Dam-de Veen G C, Kisters N, Delvoux B, van Engeland M, Herman J G, Groothuis P G

Abstract excerpt

BACKGROUND: Aberrations in mediators of Ras signaling may increase the risk of developing recurrent endometrial carcinoma. PATIENTS AND METHODS: Primary tumors of patients with (n = 44) and without (n = 44) recurrent stage I endometrioid endometrial carcinoma were compared regarding the presence of K-ras mutations (codons 12 and 13), B-raf mutations (V599), and RASSF1A gene promoter methylation. RESULTS: K-ras...

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Identifiers

PMID: 17170014
DOI: 10.1093/annonc/mdl455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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