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Article

High frequency of <i>RASSF1A</i> and <i>RARb2</i> gene promoter methylation in morphologically normal endometrium adjacent to endometrioid adenocarcinoma

8 Sept 2008

Abstract excerpt

AIMS: To identify a DNA methylation signature of endometrioid carcinoma of the endometrium (EEC) in the early stages of endometrial carcinogenesis. METHODS AND RESULTS: Archival biopsy specimens of 39 EECs, 14 cases of atypical hyperplasia (AH), 11 histologically normal endometrial tissues adjacent to EECs and 24 normal control endometrial samples were retrieved. The cases were tested by quantitative...

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Share to Endometrial and Cervical Cancer Treatments
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PMID: 18783461
DOI: 10.1111/j.1365-2559.2008.03147.x

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