Article
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2003
Cohen Yoram, Singer Gad, Lavie Ofer, Dong Seung Myung, Beller Uziel, Sidransky David
Abstract excerpt
PURPOSE: Development of adenocarcinoma (AC) of the uterine cervix, as well as squamous cell carcinoma (SCC), is strongly linked to infection by high-risk human papillomavirus (HPV) types. Human HPV E6 and E7 proteins inactivate the tumor suppressor genes p53 and retinoblastoma, respectively. Howe...
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