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Article

Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma.

Gynecologic oncology - 1 Jun 2007

Kang Sokbom, Kim Hy-Sook, Seo Sang Soo, Park Sang-Yoon, Sidransky David, Dong Seung Myung

Abstract excerpt

OBJECTIVE: Although the incidence of cervical adenocarcinoma is increasing, few genetic and epigenetic changes in its progression have been described. We hypothesized that RASSF1A methylation and KRAS and BRAF mutations may play an important role in cervical adenocarcinoma. METHODS: Archival primary carcinoma tissues (n=258) in uterine cervix consisting cervical adenocarcinomas (n=115) and squamous cell...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Genes, ras

Share to Proto-Oncogene Proteins B-raf

Share to Tumor Suppressor Proteins

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 17360030
DOI: 10.1016/j.ygyno.2007.01.045

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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